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Background: Hydroxychloroquine (HCQ) is a well-known immunomodulator that is useful as in the treatment for lupus because of its inhibitory effect on toll-like receptors and cytokines, which are speculated to play a role in the pathogenesis of Immunoglobulin A (IgA) nephropathy (IgAN). Methods Digital databases were queried to study the safety of RAASi in COVID-19. Numerous studies across diverse kidney diseases demonstrated a mean decrease or “dip” in eGFR in patients randomized to RAASi in the first 1 to 3 months followed by a less steep fall in eGFR compared with placebo, preserving kidney function with decreased end-stage kidney disease and doubling of serum creatinine. history of Bhutan, a survey of the notable events and people in the history of Bhutan. 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